Medicine

Progressing ASO treatments coming from advancement to application

.Completing interests.R.S., M.S., H.G. and A.A.R. are actually coordinators of the 1M1M project. H.G. as well as A.A.R. are actually board of supervisors participants as well as R.S., M.S. and also A.A.R. are actually members of the clinical consultatory committee of N1C. A.A.R. makes known job through LUMC, which possesses licenses on exon-skipping technology, some of which has actually been licensed to BioMarin and ultimately sublicensed to Sarepta. As co-inventor of some of these patents, A.A.R. was actually qualified to a reveal of nobilities. A.A.R. even more reveals acting as impromptu specialist for PTC Therapies, Sarepta Therapeutics, Regenxbio, Dyne Therapeutics, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and also Astra Zeneca. Before 5 years, A.A.R. also carried out ad hoc seeking advice from for Alpha Anomeric. A.A.R. likewise states registration of the scientific boards of advisers of Eisai, Hybridize Therapies, Silence Therapies, Sarepta Therapeutics, Sapreme and Mitorx. Previously 5 years, A.A.R. was likewise a scientific board of advisers participant for ProQR. Compensation for A.A.R. u00e2 s consulting and also suggesting activities is actually spent to LUMC. In the past 5 years, LUMC also got audio speaker honoraria from PTC Therapeutics, Alnylam Netherlands, Italfarmaco and Pfizer as well as financing for agreement study from Sapreme, Eisai, Galapagos, Synaffix as well as Alpha Anomeric. Project financing is actually gotten from Sarepta Therapeutics and also Entrada through unconstrained gives. H.G. has nothing at all to reveal in connection with the subject matters dealt with in this document. In the past 5 years, he has additionally obtained working as a consultant gratuity from UCB. M.S. acquired consultancy gratuity from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly as well as Solaxa before 5 years, all unconnected to the here and now document. R.S. has absolutely nothing to make known relative to the subject matters covered in this particular composition. She has received speaker and/or consultancy honoraria or sponsoring contributions from Abbvie, Bial, STADA as well as Everpharma in the past 5 years.